• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    method and device for transporting fluids to the treatment unit of a medical treatment apparatus, in particular to the dialyzer of a dialysis apparatus. the invention relates to a device and a method for transporting fluids into the treatment unit (1) of a medical treatment device, in particular, into the dialyser of a dialysis device, as well as an apparatus of treatment of extracorporeal blood. the device according to the invention and the method according to the invention are based on the fact that the fluid, with which the treatment unit is supplied, circulates in a fluid circuit (ii), including the treatment unit. for the purpose of balancing fresh and used fluid, which are supplied to the treatment unit or transported out of the treatment unit, use is made of a balance unit (5), with a balance chamber (6), which can be incorporated into the fluid circuit including the treatment unit. thus it is possible to supply the fluid circuit continuously for fresh fluid or to transport continuously out of the fluid. the supply and discharge of fresh and used fluid can be carried out at a flow rate different from the flow rate at which the fluid circulates in the fluid circuit through the treatment unit.
    公开号:BR112012032035B1
    申请号:R112012032035-1
    申请日:2011-06-14
    公开日:2020-10-06
    发明作者:Matthias Brandl；Manfred Weis；Volker Nier；Gerhard Mager；Michael Herrenbauer
    申请人:Fresenius Medical Care Deustschland Gmbh；
    IPC主号:
    专利说明:

    The invention relates to a device and a method for transporting fluids into the treatment unit of a medical treatment device, in particular, to the dialyzer of a dialysis device. In addition, the invention relates to an extracorporeal blood treatment device, in particular a dialysis device, which comprises a device for transporting fluids into the treatment unit, in particular the dialyzer, of the treatment device blood, in particular dialysis devices.
    Various types of treatment apparatus are known to comprise a treatment unit to be supplied with a fluid. Known treatment devices include, for example, blood treatment devices. During blood treatment, the patient's blood flows in an extracorporeal blood circuit through the blood treatment unit. In the case of devices for hemodialysis, hemofiltration and hemodiafiltration, the blood treatment unit is a dialyzer or filter, which is divided by a semi-permeable membrane for a blood chamber and a dialysis fluid chamber. During dialysis treatment, blood flows into an extracorporeal blood circuit through the blood chamber, while dialysis fluid flows into a dialysis fluid circuit through the dialysis fluid chamber.
    Taking into account the large amounts of exchange, there is a need for known methods and apparatus for treating blood to exact balance of the fluid removed from the patient and the fluid fed to the patient during the total treatment time. Volumetric and gravimetric balance devices belong to the prior art.
    A hemodialysis device with volumetric balance is known, for example, from DE 2 6 34 238 A1. The balancing device of the known hemodialysis device comprises a hollow body of rigid volume, which is divided by a movable partition wall in two chambers. Each chamber includes an inlet and an outlet, in which the supply lines and discharge lines for fresh and respectively used dialysis fluids are eliminated, a closing element being incorporated in each line. In addition, it is planned that the pumps to transport the fresh and used dialysis fluid, as well as a control unit, which allows a mutual filling of the two chambers.
    In order to be able to ensure a continuous flow of fluid through the dialysis fluid chamber of the dialyzer, two equilibrium chambers are connected in parallel, in practice said balance chambers supply the dialyzer alternately with fresh dialysis fluid. A balance unit with two balance chambers is known, for example, from DE 28 38 414.
    During a dialysis treatment, the flow of dialysis fluid usually amounts to 500 ml / min, but can rise to 1000 ml / min, depending on the given treatment situation.
    In the case of a dialysis period of 4 hours, this means a dialysis fluid requirement that typically corresponds to about 120 l, but depending on the given treatment situation it can also be above 200 l.
    Taking into account the great need for dialysis fluid, the preparation of the dialysate from concentrates and pure water (OR water), in the machine was established, in order to avoid the storage of very large amounts of solutions. OR water is made available centrally at the clinic and distributed via lines to dialysis machines at dialysis stations.
    In the treatment of acute renal failure, as can occur, for example, after an accident, which requires intensive care support for the patient, an OR water connection is generally not present. The dialysis fluid is then placed in the machine, using containers, for example, cans or bags.
    In order to keep handling costs low, an attempt is made, especially in the case of intensive care support for acute renal failure, to reduce the need for dialysis fluid. This is achieved by the fact that the dialysis fluid is recirculated through the dialyzer for a certain period of time. The need for dialysate can thus be reduced to values below 100 ml / min.
    A blood treatment device with a recirculation circuit is known, for example, from USA 5 685 988. The dialysis fluid recirculation should, however, be used only for the determination of blood treatment parameters.
    The problem inherent to the invention is to provide a device for transporting fluids into the treatment unit of a medical treatment device, in particular, for the dialyser of a dialysis device, with such a device the need for fluid dialysis can be reduced. Another problem of the invention is to provide a method for transporting fluids into the blood treatment unit of a medical treatment device, said method allowing a reduction in the need for fluid dialysis. The problem with the present invention is also to provide an apparatus for the extracorporeal treatment of blood with such a device for transporting fluids.
    According to the invention, the solution to these problems is realized with the characteristics of the independent claims. Advantageous embodiments of the invention are the subject of the subclaims.
    The device according to the invention and the method according to the invention are based on the fact that the fluid with which the treatment unit is supplied circulates in a fluid circuit, which includes the treatment unit. In order to balance the fresh and used fluid that is fed into the treatment unit or transported out of the treatment unit, a balance unit is used which, in principle, can comprise one or two balance chambers.
    The device according to the invention and the method according to the invention are characterized by the fact that the balance chamber of the balance unit, or the two balance chambers of the balance unit, can be incorporated into the fluid circuit, including the treatment unit. Thus, it is possible to supply fresh fluid continuously to the fluid circuit and to discharge used fluid continuously from the fluid circuit. The supply and discharge of fresh and used fluid can be carried out at a flow rate different from the flow rate at which the fluid circulates through the treatment unit in the fluid circuit. Therefore, a "fluid" is established in the fluid circuit, which, depending on the ratio between the flow rates, has a concentration between a "fresh fluid" and a "used fluid". Regardless of the supply and discharge of fresh or used fluid, the fluid (ultrafiltrate) can also be removed from the fluid circuit, including the blood treatment unit, in particular the dialyzer.
    In a preferred embodiment of the invention, the flow rate at which the fluid circulates through the treatment unit in the fluid circuit is greater than the flow rate at which the fluid is fed and discharged from the fluid circuit.
    The device according to the invention comprises a diversion that connects the discharge line leading from the balance chamber to the treatment unit to the supply line leading from the treatment unit to the balance chamber. The bypass allows not only a continuous supply of fresh fluid into the fluid circuit, including the treatment unit, but also the maintenance of a flow of fluid through the blood treatment unit, when the balance chamber of the balance unit is being filled with fresh fluid, thus displacing used fluid. If a balance chamber with two balance chambers operating alternately is used, this advantage is admittedly not exercised. A particularly preferred embodiment of the present invention thus provides a balance unit with a single balance chamber. In this particularly preferred embodiment, the bypass ensures that the flow of fluid through the blood treatment unit is not interrupted during switching between the balance chambers. A simplified design of the balance unit thus works.
    The means for transporting fluid into or out of the balance chamber and the means for interrupting the supply of fluid into the balance chamber and discharging fluid out of the balance chamber can be designed differently. Known occlusion pumps, in which hose lines can be inserted, are preferably used for transporting fluids. For interrupting the supply or discharge of fluid, it is preferable to make use of the known closing elements operated electromagnetically or pneumatically, which are arranged in the lines. The control unit controls the means for transporting fluids and the means for interrupting fluid supply or discharge. Since occlusion pumps tighten the hose line in the standstill state, occlusion pumps can also replace closing elements.
    In a particularly preferred embodiment, the means for transporting fluid comprises a first pump, which is arranged on the supply line leading from the fluid source to the balance chamber. In addition, the means of transport comprise two additional pumps, which are arranged on the discharge line leading from the balance chamber to the blood treatment unit. Of these two pumps, one is arranged in the section of this discharge line that leads to the point at which a bypass connection is connected to the discharge line, while the other pump is arranged in the section of this discharge line that leads away from the point bypass connection. The flow rates of these two pumps in the discharge line determine the flow rate at which fresh fluid is fed to the fluid circuit and used fluid is transported outside the fluid circuit.
    In a particularly preferred embodiment, the means for interrupting the supply and / or discharge of fluid comprises a first closing element, which is arranged on the first supply line leading from the fluid source to the balance chamber, a second element closing element, which is disposed in the second discharge line leading out of the balance chamber and leading to the drain, a third closing element which is disposed in the second discharge line leading out of the balance chamber and leading to the unit for blood treatment, and a fourth closing element, which is arranged on the second supply line leading from the treatment unit to the balance chamber. All closing elements are controlled by the control unit.
    In the particularly preferred embodiment, the control unit is designed in such a way that the first and second closing elements are opened and the third and fourth closing elements are closed in a first working stage of a first working cycle of working cycles successive, the first and third pumps are in operation. In the first stage of work, the balance chamber is filled with fresh fluid, the fluid used being thus displaced. During the process of filling the balance chambers, the flow of fluid through the treatment unit is not interrupted. The first work step is followed by a second work step, in which the first and second closing elements are closed and the third and fourth closing elements are open, the second and third pumps being in operation. In the second and second stage, the fluid circulates in the fluid circuit, including the blood treatment unit. Fresh fluid can also be, but does not have to be, fed into the fluid circuit or transported out of the fluid circuit.
    A preferred additional embodiment provides for integration an additional closing element in the bypass. This closing element serves for better filling and ventilation of the system, before the treatment is carried out. On the other hand, circulation in the fluid circuit can also be interrupted by means of the closing element in the bypass.
    Examples of the embodiment of the invention are explained in detail below with reference to the drawings. In the figures:
    Fig. 1 shows a hemodialysis device, with a device for providing the dialyser of the dialysis device with dialysis fluid in a very simplified schematic representation, in which the first work step of the work cycle is represented,
    Fig. 2 shows the hemodialysis device of fig. 2, in which the second work stage of the work cycle is represented,
    Fig. 3 shows a second example of the modality of the hemodialysis device, with the device for supplying the dialyzer with the dialysis fluid in a very simplified schematic representation,
    Fig. 4 shows an alternative embodiment of the hemodialysis device of fig. 3,
    Fig. 5 shows an additional example of a dialysis device modality, in a very simplified and
    Fig. 6 shows an alternative embodiment of the dialysis device of fig. 5.
    The invention is described below using the example of a blood treatment apparatus, which comprises a dialyzer as a blood treatment unit. Fig. 1 shows the main components of the hemodialysis equipment in a very simplified schematic representation. The device for supplying the dialyser with the dialysis fluid is a component part of the dialysis device.
    The dialysis device comprises a dialyzer 1, which is divided by a semi-permeable membrane (not shown) in a blood chamber (not shown) and a dialysis fluid chamber. A blood supply line 2, in which a blood pump 3 is incorporated, leads from the patient to an inlet IA of the blood chamber of the dialyzer 1, while a blood discharge line 4, which leads to the patient, leads out of an outlet 1B of the dialyzer 1 blood chamber. During blood treatment, the patient's blood flows in the extracorporeal blood circuit I through the dialyser 1 blood chamber.
    Dialyzer 1 is fed with dialysis fluid, which flows through the dialysis fluid chamber of dialyser 1. The device for transporting dialysis fluid in dialyser 1 is described below.
    For the balance of fresh dialysis fluid against dialysis fluid used, use is made of a balance unit 5, which, in the present example of embodiment, comprises only a balance chamber 6. The balance chamber 6 comprises a first inlet 6A at the bottom and a first outlet 6B at the top, as well as a second entry 6C at the bottom and a second outlet 6D at the top.
    The dialysis fluid is provided in a dialysis fluid source 7, which can be a container or a bag. Leading out of the fluid dialysis source 7 has a first supply line 8, which leads to the first inlet 6A of the balance chamber 6. Leading out of the first outlet 6B of the balance chamber 6 has a first line of the first 9, leading to a drain 32. Incorporated into the first supply line 8 is a blood pump 10, in particular an occlusion pump, which carries fresh dialysis fluid from the dialysis fluid source 7 to the balance chamber 6.
    Leading out of the second outlet 6D of the balancing chamber 6 there is a second discharge line 11, which leads to the inlet 1C of the dialysis fluid chamber of the dialyzer 1. Leading out of the 1D of the dialysis fluid chamber of the dialyzer 1 there is a second second supply line, which leads to the second entry 6C of the balance chamber 6.
    Supply and discharge lines 8, 9, 11, 12 are hose lines. The second discharge line 11 comprises, in the flow direction, a first section 11A and a second section 11B, while the second supply line 12 comprises, in the flow direction, a first section 12A and a second section 12B.
    The second discharge line 11 and the second supply line 12 are connected via a diversion 13. Bypass 13 is a line that is connected with one end to the junction point 11C between the first section 11A and the second section 11B of the second discharge line 11 and with the other end to the junction point 12C between the first section 12A and the second section 12B of the second supply line 12. A fluid circuit II, which includes the dialysis fluid chamber of the dialyzer 1, is created with bypass 13. Fluid circuit II comprises bypass line 13, second section 11B of the second discharge line 11, the dialysis fluid chamber of the dialyzer 1 and first section 12A of the second supply line 12.
    A second pump 14 is incorporated into the first section 11A of the second discharge line 11 and a third pump 15 is incorporated into the second section 11B of the second discharge line 11. Leading out of the first section 12A of the second supply line 12 there is a line ultrafiltrate 16, in which a fourth pump 17 is incorporated, with which the fluid (ultrafiltrate) can be removed from the fluid circuit II. The four pumps 10, 14, 15, 17 are connected via control lines 10 ', 14', 15 ', 17' to a control unit 18. In the present example, control unit 18 is part of a component the central control unit of the dialysis device. Central control unit 18 of the dialysis device is also connected to the blood pump 3 via a control line 3 '.
    A first closing element 19 is incorporated in the first supply line 8 between the first pump 10 and the balancing chamber 6, while a second closing element 20 is incorporated in the first discharge line 9. A third closing element 21 is incorporated to the second discharge line 11 between the balance chamber 6 and the second pump 14, while a third closing element 22 is incorporated into the second supply line 12 between the junction point 12C and the balance chamber 6. Closing elements 19 , 20, 21, 22 are electromagnetically operated hose clamps, which are connected via control lines 19 ', 20', 21 ', 22' to the central control unit 18.
    Central control unit 18 controls pumps 10, 14, 15 as follows. The dialysis device is operated in successive cycles, which comprise every two work steps. Fig. 2 shows the first work step and fig. 2, the second work stage of a work cycle.
    The first work step comprises filling the equilibrium chamber 6, while the dialysis fluid is flowing through the dialyzer 1. The central control unit 18 opens the first and second closing elements 19, 20 and closes the third and fourth elements closing 21, 22. The Control Unit 18 thus puts the first pump 10 and the third pump 15 into operation. Second pump 14 is on standby. Since the second occlusion pump 14 is on hold, the third closing element 21 can also be opened.
    The first pump 10 conveys fresh dialysis fluid out of the dialysis fluid source 7 to the balance chamber 6, which was previously filled with dialysis fluid used in the second working step of the preceding duty cycle. While the balancing chamber 6 is being filled with fresh dialysis fluid, the dialysis fluid used is moved through a first discharge line 9 to drain 32. The first pump 10 runs until the dialysis fluid used has been completely replaced by the fresh dialysis fluid in the balance chamber 6. During the filling of the balance chamber 6 with fresh dialysis fluid, the flow of fluid through the dialyzer 1 is not interrupted. The third pump 15 carries the dialysis fluid in the fluid circuit II, which includes the second section 11B of the second discharge line 11, the dialyzer 1, the first section 12A of the second supply line 12 and the bypass line 13. A Balance chamber 6 should be filled, as quickly as possible, with fresh dialysis fluid, so that the dialysis fluid circulates for only a short period in the fluid circuit (fig. IA).
    The first work step (fig. 1) is followed by the second work step (fig. 2). The central control unit 18 closes the first and second closing elements 19, 20 and opens the third and fourth closing elements 21, 22 in the second work step. In addition, the control unit 18 stops the first pump 10 and puts the second pump 14 into operation. Consequently, the second and third pumps 14, 15 are in operation. Control unit 18 selects a lower delivery rate for the second pump 14 than for the third pump 15. Therefore, the dialysis fluid flows in the fluid circuit II at a flow rate that corresponds to the difference between the flow rates of the third and second pumps 15, 14. This QDfast flow rate can be relatively high.
    While dialysis fluid is circulating in fluid circuit II through dialyzer 1, fresh dialysis fluid is constantly fed to fluid circuit II and used dialysis fluid removed from fluid circuit 12. Fresh dialysis fluid is fed to circuit of fluid II at a pre-selected delivery rate via the second pump 14 through the first section 11A of the second discharge line 11, which is connected to the second outlet 6D of the balance chamber 6. The dialysis fluid used is withdrawn from the fluid circuit II via the second section 12B of the second supply line 12, which is connected to the second inlet 6C of the balance chamber 6. The dialysis apparatus also allows the fluid (ultrafiltrate) to be removed from the fluid circuit II. The control unit 18 starts the ultrafiltration pump 17 in order to carry out the ultrafiltration.
    Depending on the flow rates of the second and third pumps 14, 15, fresh dialysis fluid can be supplied continuously over a relatively short or relatively long period of time and the desired ratio of fresh dialysis fluid to that used in fluid circuit II can be adjusted.
    The second working stage (fig. 2) of the working cycle is then again followed by the first working stage (fig. 1) of each subsequent cycle.
    Fig. 3 shows a second example of a dialysis device modality, which differs from the modality described with reference to figs. 1 and 2 just because a fifth locking element 23, which is also operated by the central control unit 18, is incorporated in the bypass line 13. The parts corresponding to each other are therefore provided with the same numbers of reference. Closing element 23 on the bypass line 13 is, in principle, opened during operation of the dialysis device. The closing element 23 can, however, also be closed in order to interrupt the circulation of the dialysis fluid in the fluid circuit II.
    Closing element 23 in the bypass line 13 is closed for filling and venting the fluid system, so that the flow of fluid through the bypass line is interrupted. In addition, the second closing element 20 is closed, so that the fluid cannot pass to the drain 32. The fluid is fed through a first supply line 8 to the balance chamber 6, while the pump 10 is running . When pumps 14 and 15 are in operation, fluid can flow through the second discharge line 11, dialyzer 1 and second supply line 12. For ventilation purposes, a ventilation valve 33 is provided on the upper side of the balance chamber 6, which is shown only in outline in fig. 3.
    Fig. 4 shows an alternative embodiment of the dialysis device of fig. 3. The example of the embodiment of fig. 4 differs from the embodiment of fig. 3 only by routing the second discharge line 11 and the second supply line 12 and the length of the bypass line 13. The parts corresponding to each other are again provided with the same reference numbers. In order to reduce the dead volume, in which air can accumulate when the fluid system is being filled, the second discharge line and supply line 11, 12 are routed directly to the connections of the closing element 23, in so that the bypass volume 13 can be reduced to a minimum.
    The device according to the invention for supplying dialysis fluid to the dialyzer has the advantage that a balance unit with two balance chambers can be dispensed with. It is possible, even with a balancing unit comprising only a balancing chamber to maintain a continuous flow of dialysis fluid through the dialyzer while balancing the fresh dialysis fluid with the dialysis fluid used.
    For the sake of completeness, fig. 5 shows a dialysis device, with two balancing chambers 6A, 6B, which are connected in parallel and which operate alternately. The embodiment example of fig. 5 differs from the embodiment of figs. 1 and fig. 2 in that the second balancing chamber 6B with respective supply and discharge lines 24, 25, 26, 27, within which closing elements 28, 29, 30, 31 are respectively incorporated, is connected in parallel to the first balance chamber 6A. The balance unit 6 with two balance chambers 6A, 6B is operated in a known manner, as described for example in DE 28 38 414.
    Fig. 6 shows another example of modality, which differs from the modality of fig. 4 solely because the balance chamber 6 is divided by a flexible partition wall 6G in a first half of chamber 6E and a second half of chamber 6F. In this embodiment, the first input 6D and the second output 6A are connected to the first half of chamber 6E, while the second input 6C and the first output 6B are connected to the second half of chamber 6F. In this embodiment, the two chamber halves 6E and 6F of the balance chamber 6 are alternately filled with fresh and used dialysis fluid. The parts that correspond to each other are again provided with the same reference numbers. In this modality, too, fluid circuit II allows the dialysis fluid flow through dialyser 1 to be maintained during filling of the equilibration chamber with fresh dialysis fluid 6. When one of the two halves of chamber 6E or 6F is being Filled with fresh dialysis fluid, the used dialysis fluid is displaced from the respective other half of the 6F or 6E chamber.
    权利要求:
    Claims (11)
    [0001]
    1. Device for transporting fluid into the treatment unit of a medical treatment device with a balancing unit (5) comprising at least one balancing chamber (6), a first supply line (8) leading to the balance chamber for supplying fluid from a fluid source (7) into the balance chamber and a first discharge line (9) leading out of the balance chamber to discharge fluid from the balance chamber for the drain (32), a second discharge line (11) leading out of the balance chamber for the discharge of the fluid from the balance chamber to a treatment unit (1) and a second supply line ( 12) leading to the balance chamber for supplying fluid from the treatment unit to the balance chamber, means (10, 14, 15) for transporting fluid into and / or outside the balance chamber and means ( 19, 20, 21, 22) for int erupt the fluid supply into the balance chamber and / or the discharge of fluid from the balance chamber, a control unit (18) to control the means (10, 14, 15) for the transport of fluid and means (19, 20, 21, 22) to interrupt the supply and / or discharge of fluid, a bypass (13) connects the second discharge line (11) to the second supply line (12), which is designed in such a way so that a fluid circuit (II) including the treatment unit (1) is created, thus deviating completely or partially from the balance chamber (6), in which the second discharge line (11) comprises, in a first and second section (11A, 11B) in the flow direction and the second supply line (12) comprises a first and a second section (11A, 11B) in the flow direction, and a bypass connection (13) is connected to the junction (11C) between the first and second section of the second discharge line and the other bypass connection is connected to the point junction (12C) between the first and the second section of the second supply line, and characterized by the fact that the medium for transporting fluid comprises a second pump (14), which is arranged in the first section (11A) of the second discharge line (11), and a third pump (15), which is arranged in the second section (11B) of the second discharge line (11).
    [0002]
    2. Device according to claim 1, characterized by the fact that the means (10, 14, 15) for the transport of fluid and means (19, 20, 21, 22) for interrupting the supply and / or discharge fluid flows are designed in such a way that a fluid flow in the fluid circuit (II), including the treatment unit (1), can be adjusted to a predetermined flow rate.
    [0003]
    3. Device, according to claim 2, characterized by the fact that the control unit (18) is designed in such a way that, in a first working stage of a first working cycle of successive working cycles, the control chamber balance (6) is filled by means of the first supply line (8) with the fluid from the fluid source (7), the fluid thus being displaced out of the balance chamber through the first discharge line (9 ) to the drain (32), through which the fluid circulates in the fluid circuit (II), including the treatment unit bypassing the balance chamber completely, and, in a second working step of successive work cycles, the fluid it is transported out of the balance chamber (6) through the second discharge line (11) and the fluid is fed to the balance chamber through the second supply line (12), through which the fluid circulates in the fluid circuit ( II), including the treatment unit ment.
    [0004]
    Device according to any one of claims 1 to 3, characterized in that the means for transporting fluid comprises a first pump (10), which is arranged in the first supply line (8).
    [0005]
    Device according to any one of claims 1 to 4, characterized in that the means 20 for interrupting the supply and / or discharge of fluid comprises: a first closing element (19) disposed in the first supply line (8), a second closing element (20) disposed on the first discharge line (9), a third closing element (21) disposed on the second discharge line (11), a fourth closing element (22) disposed on the second supply line (12).
    [0006]
    Device according to any one of claims 1 to 5, characterized in that the means for transporting fluid and means for interrupting the supply and / or discharge of fluid comprise a fifth closing element (23), which is arranged in diversion 5 (13).
    [0007]
    7. Device according to claim 5 or 6, characterized in that the control unit (18) is designed in such a way that the first and second closing elements (19, 20) are opened and the third and fourth closing elements (21, 22) are closed in a first working stage of a first working cycle of successive working cycles, the first and third pumps (10, 15), in operation, and the first and second closing elements (19, 20) are closed and the third and fourth closing elements (21, 22) are open in a second work stage of successive work cycles, the second and third pumps (14, 15) being in operation.
    [0008]
    8. Device according to claim 7, characterized by the fact that the control unit (18) is designed in such a way that the second and third pumps (14, 15) are operated in different delivery modes in the second stage of job.
    [0009]
    9. Device according to claim 7 or 8, characterized by the fact that the control unit (18) is designed in such a way that the third pump (15) is operated in the second work step according to a delivery speed , which is higher than the delivery rate of the second pump (14).
    [0010]
    10. Apparatus for the treatment of extracorporeal blood characterized by the fact that it is with a device as defined in any one of claims 1 to 9.
    [0011]
    11. Apparatus for the treatment of extracorporeal blood, according to claim 10, characterized by the fact that the apparatus for treating blood is a dialysis device, the blood treatment unit being a dialyzer (1).
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    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    DE2634238A1|1976-07-30|1978-02-02|Berghof Forschungsinst|Dialysis liquor substitution in blood dialysis - uses cells with flexible membranes to allow balanced replacement|
    DE2838414C2|1978-09-02|1984-10-31|Fresenius AG, 6380 Bad Homburg|Device for hemodialysis and for withdrawing ultrafiltrate|
    US4209391A|1978-11-06|1980-06-24|Cordis Dow Corp.|Apparatus and method for automatically controlling hemodialysis at a pre-selected ultrafiltration rate|
    FR2680975B1|1991-09-10|1998-12-31|Hospal Ind|ARTIFICIAL KIDNEY WITH MEANS FOR DETERMINING A SUBSTANCE IN BLOOD.|
    DE4239937C2|1992-11-27|1995-08-24|Fresenius Ag|Method for determining the functionality of a partial device of a hemodialysis machine and device for carrying out this method|
    US5685988A|1993-09-15|1997-11-11|Malchesky; Paul|Dialysis process and system|
    IT1260992B|1993-10-15|1996-04-29|Hospal Dasco Spa|MACHINE FOR EXTRA-BODY DIALYSIS.|
    JP3892921B2|1996-11-19|2007-03-14|東レ・メディカル株式会社|Hemodialysis machine|
    DE19702211A1|1997-01-23|1998-07-30|Polaschegg Hans Dietrich Dr|Haemodialysis appts|
    DE19708391C1|1997-03-01|1998-10-22|Fresenius Medical Care De Gmbh|Method and device for ultrafiltration in hemodialysis|
    DE29902953U1|1999-02-19|2000-07-13|Fresenius Medical Care De Gmbh|Device for dialysis treatment|
    JP4093695B2|1999-02-19|2008-06-04|フレセニウス・メディカル・ケア・ドイッチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング|Dialysis treatment device|
    EP2005982B1|2007-06-20|2010-08-18|B. Braun Avitum AG|Apparatus for determining the reduction ratio or the Kt/V value of a kidney substitution treatment|
    US9101716B2|2008-02-01|2015-08-11|Baxter International Inc.|Multi-pass dialysis|EP2739325B1|2011-08-02|2017-10-04|Medtronic, Inc.|Hemodialysis system having a flow path with a controlled compliant volume|
    ES2534477T5|2012-05-09|2018-07-20|D_Med Consulting Ag|Procedure for priming a hemodialysis device|
    US10089443B2|2012-05-15|2018-10-02|Baxter International Inc.|Home medical device systems and methods for therapy prescription and tracking, servicing and inventory|
    US9713666B2|2013-01-09|2017-07-25|Medtronic, Inc.|Recirculating dialysate fluid circuit for blood measurement|
    US10010663B2|2013-02-01|2018-07-03|Medtronic, Inc.|Fluid circuit for delivery of renal replacement therapies|
    US10850016B2|2013-02-01|2020-12-01|Medtronic, Inc.|Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection|
    US9623164B2|2013-02-01|2017-04-18|Medtronic, Inc.|Systems and methods for multifunctional volumetric fluid control|
    DE102013019356A1|2013-11-19|2015-06-03|Fresenius Medical Care Deutschland Gmbh|Apparatus and method for balancing fluids for an extracorporeal blood treatment device|
    US10537875B2|2013-11-26|2020-01-21|Medtronic, Inc.|Precision recharging of sorbent materials using patient and session data|
    US9884145B2|2013-11-26|2018-02-06|Medtronic, Inc.|Parallel modules for in-line recharging of sorbents using alternate duty cycles|
    DE102013021012A1|2013-12-13|2015-06-18|Fresenius Medical Care Deutschland Gmbh|Device for extracorporeal blood treatment|
    DE102014003619A1|2014-03-13|2015-09-17|Fresenius Medical Care Deutschland Gmbh|Apparatus and method for balancing an inflow and outflow from a medical treatment device|
    WO2015199766A1|2014-06-24|2015-12-30|Medtronic, Inc.|Modular dialysate regeneration assembly|
    EP3160534A4|2014-06-24|2018-03-07|Medtronic Inc.|Stacked sorbent assembly|
    CN105727382B|2016-01-28|2017-12-22|龚德华|A kind of continous way CRRT machine capability bascules of two tripper|
    RU2729725C2|2016-03-14|2020-08-11|Хепа Уош Гмбх|Systems or devices and methods of dialysis|
    US10981148B2|2016-11-29|2021-04-20|Medtronic, Inc.|Zirconium oxide module conditioning|
    US11213616B2|2018-08-24|2022-01-04|Medtronic, Inc.|Recharge solution for zirconium phosphate|
    法律状态:
    2018-12-26| B06F| Objections, documents and/or translations needed after an examination request according art. 34 industrial property law|
    2019-09-17| B06U| Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure|
    2020-05-12| B09A| Decision: intention to grant|
    2020-10-06| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/06/2011, OBSERVADAS AS CONDICOES LEGAIS. |
    优先权:
    申请号 | 申请日 | 专利标题
    DE102010023635.7|2010-06-14|
    DE201010023635|DE102010023635A1|2010-06-14|2010-06-14|Device and method for conveying liquids into the treatment unit of a medical treatment device, in particular into the dialyzer of a dialysis machine|
    PCT/EP2011/002915|WO2011157396A1|2010-06-14|2011-06-14|Method and device for delivering liquids into the treatment unit of a medical treatment device, in particular into the dialyser of a dialysis device|
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